Robotic system for three-dimensional culture on curved surfaces using galvanotaxis for the generation of tissues from animal cells

Abstract

Due to the great need to improve the methods of bioprinting processes, the implementation of bioprinting in curved surfaces is needed to reassemble the idea of 3D bioprinting and generate a novel system that could create more complex 3D structures than the ones created by 3D bioprinting in planar surfaces. This work focuses on analyzing the theory needed to implement this nonplanar system in order to develop a successful design that promote the aggregation of cells in a nonplanar surface and maintain the cell’s life. Being able to implement a 3D bioprinting system in curved surfaces is going to help others to design and print more complex structures such as organs with high vascularity. The expected results of this work are to create a prototype based on two dc motors, which allows motion in x and y axis. One of the future possible applications of this prototype is to improve the advancements in the tissue engineering area in order to print more complex structure as the apex of the heart, kidneys and neural tissue.