Ciencias Exactas y Ciencias de la Salud

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Using competitive and technology intelligence to determine 4D printing technology advances in health considering design factors and applications.
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2023-05) Martínez de Anda, Angelica Anette; RODRIGUEZ SALVADOR, MARISELA; 20562; Rodríguez Salvador, Marisela; puemcuervo, emipsanchez; Bourguet Díaz, Rafael Ernesto; Smith Cornejo, Neale Ricardo; School of Engineering and Sciences; Campus Monterrey
Currently there is an increasing demand in the medical field for low-cost, high-quality products as well as personalized solutions, and different manufacturing methods are being investigated to provide innovative solutions. Four-dimensional (4D) printing is a promising technology to solve challenges associated with applications of 4D printing in regenerative medicine and biomedical devices. A revolution is expected to come in this regard, and it is essential to keep abreast of the latest developments. Under this context, the purpose of this thesis is to determine 4D printing technology advances in the medical field, considering design factors and applications, using a Competitive Technology Intelligence (CTI) methodology. For this aim, publications were analyzed from the Scopus database between January 1, 2017, and May 9, 2023. The main trends were identified for both Design Factors and Applications. In the first case, the following were considered: 4D printing methods, external stimuli, materials, mathematical models, interaction mechanisms, and deformation mismatch, while in the second case, the applications of 4D printing involved were considered: drug delivery systems, stents, and scaffolds. The obtained Design Factors results included improvements in mechanical properties of hydrogels by adding magnetic nanoparticles, bio-polyurethan, and other materials, the development of cell-friendly bioprinting methods to print cellular structures, and the use of theoretical-experimental approaches to predict shape deformation of structures. While for Applications, results included advances in the development of expandable drug delivery systems, fabrication of stents for treatment of vascular and tracheal stenosis, and the design of scaffolds for the treatment of cartilage defects and bone regeneration. This research contributes to researchers, academics, and companies involved in Research and Development (R&D) and Innovation looking for new solutions to improve health incorporating breakthrough technologies such as 4D printing.
4d printing research trends and applications in the medical field: a scientometric analysis
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-07-28) Padilla Aguirre, Karen Marcela; RODRIGUEZ SALVADOR, MARISELA; 20562; Rodríguez Salvador, Marisela; emijzarate, emipsanchez; Urbina Coronado, Pedro Daniel; Elizondo Noriega, Armando; Escuela de Ingeniería y Ciencias; Campus Monterrey
Innovation plays a key role on a company’s either success or failure. But innovation is not just the creating or adopting new technologies; it is also directly connected with a solid strategic planning. Competitive technology intelligence is based on the systematic and ethical process of gathering, analyzing and transforming information into actionable knowledge. It aims to support decision making and strategic planning, because the knowledge produced by this methodology constitutes an early warning for research, development and innovation [19]. Three-dimensional (3D) printing is a technique of additive manufacturing that has revolutionized engineering, product design and manufacturing, as it allows the rapid conversion of digital 3D model information into physical static objects [45]. However, in the last few years a new possibility has been introduced to add ’time’ as a new dimension to create 4D printing. The medical field keeps changing and progressing at a high speed with new technologies emerging every day. 4D printing on the medical field is an area where it is necessary to provide decision makers with an overview of technological knowledge that helps them generate innovation opportunities. On this thesis, a Competitive technology intelligence approach was executed to identify trends in 4D printing technologies applied to the medical field, in order to provide relevant information through a technological landscape to support decision makers to uncover innovation opportunities. The results of the analysis revealed that most of the research developed is on the materials category, which relates completely to the fact that smart materials are the key difference between 3D and 4D printing. Most of the researches focus on shape memory polymers, hydrogels and liquid crystal elastomers. On the processes category researched is focused on the physical configuration of the printing model, printing parameters and adapting machines to modify the printing configurations. As for the applications, three main subcategories were identified, hollow tubes/stents, tissue engineering and drug delivery. According to the growth kinetics it is a field that although is fairly new, keeps growing and will keep gaining attention.

Ciencias Exactas y Ciencias de la Salud

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