Ciencias Exactas y Ciencias de la Salud
Permanent URI for this collectionhttps://hdl.handle.net/11285/551039
Pertenecen a esta colección Tesis y Trabajos de grado de las Maestrías correspondientes a las Escuelas de Ingeniería y Ciencias así como a Medicina y Ciencias de la Salud.
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- Development and automation of a scaled manufacturing cell based on regulation control(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2023-06-20) Contreras Baeza, Alonso; VAZQUEZ TOPETE, CARLOS RENATO; 166163; Vázquez Topete, Carlos Renato; emipsanchez; Ramírez Treviño, Antonio; Navarro Gutiérrez, Manuel; School of Engineering and Sciences; Campus MonterreyThis thesis is an approach focused on industrial automation for complex manufacturing systems, which generally involves a set of devices, such as sensors and actuators in charge of executing certain tasks commanded by one or more Programmable Logic Controllers (PLCs). It is known that, as more devices and new technologies are integrated, such systems are more complex to control. Said automation systems can be represented by the use of formal methods, like occurrence of events, or better called as discrete event systems (DES). Regulation Control is a proposed approach to model and control discrete event systems based on Interpreted Petri Nets, which are a graphical and mathematical modeling graph that can help to represent and analyze such discrete event systems. In order to test the functionality of this Regulation Control approach, in this thesis is proposed to design, manufacture, assemble, integrate, communicate and control 3 workstations from a scaled manufacturing cell. It is expected that by implementing Regulation Control methodologies, PLCs can control the workstations by interpreting the Interpreted Petri Nets from the software RC-Petri, which is communicated through Modbus and a simple signal identification program, without the need of creating an extensive program. In turn, it is intended to test the deadlock-freeness and its practical implementability assuring a safe operation of each workstation using a General Functional Testing.
- Development of a wirelessly-controlled electrolysis pump for automation of bioanalytical assays in Centrifugal Microfluidic Devices(Instituto Tecnológico y de Estudios Superiores de Monterrey) Romero-Soto, Fabian Oswaldo; https://orcid.org/0000-0002-2996-0860; 885739; Martinez-Chapa, Sergio Omar; Martínez López, José Israel; Gallo Villanueva, Roberto Carlos; Campus Monterrey; Campus Monterrey; Campus Monterrey; Aeinehvand, Mohammad MahdiBioanalytical assays for diagnosis of infectious diseases are typically performed in sophisticated labs with highly trained technicians. Unfortunately, these labs are not accessible to everybody because the service is either expensive or far from the patients in unprivileged and remote areas. Reaching millions of people, particularly in the rural environment of developing countries needs more affordable technologies. Centrifugal Microfluidic Devices have been used to automate complex bioanalytical assays and the technology has reached good maturity. However, incorporation of other techniques to manipulate the fluid, aside from the centrifugal forces, will increase the applicability of the technology for “Point-of-Care” diagnosis. Particularly, the availability of small-footprint pumps able to supply specific amounts of fluid during the different assay steps will allow integration of much more complex assays in a single disc. Conveniently, recent electrification of centrifugal microfluidic devices has opened the possibility to incorporate electrical and electrochemical sensors and actuators to the discs, which can even be controlled wirelessly. This work presents the design and implementation of a wirelessly-controlled electrolysis pump for centrifugal microfluidics platforms. By applying an electrical current to water in a chamber, electrolysis and subsequence accumulation of gases create a pneumatic pressure that enables the supply of specific fluid volumes during the different stages of complex assays. As a proof of concept, a centrifugal microfluidic device with a series of electrolysis pumps has been developed to automate a peptides-microarray-based immunoassay for the detection of influenza Hemagglutinin (HA) proteins.