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On the effect of insulator structures in electrokinetically driven microfluidic devices
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2025) Martínez González, Vania Guadalupe; Pérez González, Víctor Hugo; emimmayorquin, emipsanchez; Martínez López, José Israel; Roberts Ugrinovic, Ricardo Esteban; Gallo Villanueva, Roberto Carlos; School of Engineering and Sciences; Campus Monterrey
Within insulator based electrokinetically driven microfluidic devices (iEK, or iDEP) field, it is worth predicting the distribution of the electric field that a specific microchannel will have when voltage is applied. The electric field distortion is provoked by the presence of insulator pillars arranged in certain dispositions with the aim of manipulating particles (for instance, polystyrene beads, bacteria, cells, exosomes, etc.). Commonly, researchers simulate microchannel geometry in a finite element method (FEM) based software. Despite accurateness, this approach is costly and time consuming; this creates delays in the design process. This work provides an easy use analytical model based on electric circuit theory. The present tool calculates voltage and electric field profiles along a centered cut line throughout a microchannel. The circuit model was validated using FEM-based software and applied to an experimental case. Experimental case was an effort of reducing voltage requirement to achieve particle trapping. For that purpose, three designs of direct current insulator based electrokinetically driven (DC-iEK) microfluidic devices were used. The target geometries were two triangles forming a single constriction. Devices were stimulated using 9 V alkaline batteries and tested with 2 µm fluorescent polystyrene particles. The minimum voltage at which particle trapping was observed was 18 V.

Ciencias Exactas y Ciencias de la Salud

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