Vázquez Lepe, Elisa VirginiaVilla Carrillo, Karla Marcela2021-11-182021-11-182020-12-022020-12-08Villa Carrillo, K. M. (2020). Design and fabrication of transdermal microneedle inserts by Stereolithography for Ultrasonic Injection Molding. (Tesis de Maestría). Instituto Tecnológico y de Estudios Superiores de Monterrey. Recuperado de: https://hdl.handle.net/11285/641840https://hdl.handle.net/11285/641840https://orcid.org/0000-0002-1228-9636In this work design of a transdermal microneedle patches with hexagonal and squared cross-sections are explored using stereolithography for manufacturing ultrasonic injection molding inserts. A multi-cavity mold was designed using Finite Element Method based software, where polypropylene injection molding simulations were performed for design optimization. Manufacture of the proposed device was assessed using a stereolithography based additive manufacturing equipment suitable for high temperature applications. Dimensional accuracy was evaluated using three-dimensional metrology. Deviational height errors of 18.05% and 39.21% were found for the hexagonal and square microneedle insert cavities. A successful proof-of-concept ultrasonic injection molding is a step forward for manufacturing of microneedles for the point-of-care.TextoengopenAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0INGENIERÍA Y TECNOLOGÍA::CIENCIAS TECNOLÓGICAS::TECNOLOGÍA MÉDICA::INSTRUMENTOS MÉDICOSScienceTesis de maestríahttps://orcid.org/0000-0002-2072-4669MicroneedleStereolithographyUltrasonic Injection MoldingInsertPatch968758