González Rayas, José ManuelHernandez Hernandez, Jose AscenciónLopez Sanchez, Rosa del CarmenRayas Gomez, Ana LiliaGonzalez Yanez, Jose ManuelJerjes Sanchez, Carlos2021-06-142021-06-142021-05-04Gonzalez-Rayas, J. M., Hernandez-Hernandez, J. A., Lopez-Sanchez, R. D. C., Rayas-Gomez, A. L., Gonzalez-Yanez, J. M. & Jerjes-Sanchez, C. (2021, May 4-5). Exploration of a novel mechanism of cardiac troponin release: in silico evidence of non-classical secretion [Poster presentation]. PDB50: A Special Symposium Celebrating the 50th Anniversary of the Protein Data Bank.https://hdl.handle.net/11285/637236Cardiac troponin is one of the most important biomarkers in cardiology. Traditionally, it has represented a biochemical sign of necrosis, a characteristic of acute myocardial infarction (AMI). However, with the arrival of high-sensitivity detection assays, cardiac troponin is now detected in healthy patients and in a number of uncommon scenarios unrelated to AMI (such as strenuous exercise, rapid atrial pacing and COVID-19). This suggests that troponin could be released as a consequence of alternative processes other than the well-stablished necrotic cell death.TextoengopenAccesshttp://creativecommons.org/licenses/by-nc/4.0BIOLOGÍA Y QUÍMICAMEDICINA Y CIENCIAS DE LA SALUDMedicineItem publicado en memoria de congresohttps://orcid.org/0000-0003-3035-6609troponinnon-classical secretionhigh-sensitivity cardiac troponin assaysexosomesmicrovesicles1757557216406728